Cheap Generic Neurontin (Gabapentin) Online – Manual

Cheap Generic Neurontin (Gabapentin) Online – Manual
Generic Neurontin (Gabapentin)

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What is Neurontin?

Neurontin, also known by its generic name gabapentin, is a medication that belongs to the class of anticonvulsant drugs. It was initially developed to treat epilepsy, specifically partial seizures. However, over time, this has also been approved for the management of other conditions such as neuropathic pain and is used off-label for various other indications.

It is available in various oral forms, including capsules, tablets, and oral solutions, allowing for flexibility in dosing and administration. The dosage and duration of treatment are determined by healthcare professionals based on individual needs and medical conditions.

While this drug is generally well-tolerated, it can cause side effects such as drowsiness, dizziness, fatigue, and peripheral edema. It’s important to follow the prescribed dosage and consult with a healthcare provider if any concerns or adverse effects arise.

Classification

Neurontin (gabapentin) is classified as an anticonvulsant or antiepileptic medication. It falls within the pharmacological class of drugs that are primarily used to prevent or control seizures in individuals with epilepsy.

However, rhis medicine has also been approved for additional medical conditions beyond epilepsy. It is commonly prescribed for the management of neuropathic pain, such as diabetic neuropathy or postherpetic neuralgia, which refers to nerve pain caused by diabetes or shingles, respectively. Neurontin is also used off-label for various other conditions, including restless leg syndrome, fibromyalgia, and certain anxiety disorders.

By modulating neurotransmitters and affecting electrical activity in the brain, Neurontin helps to reduce abnormal neuronal firing and stabilize the excitability of neurons. This mechanism of action contributes to its anticonvulsant effects and the alleviation of neuropathic pain.

What is neurontin generic name?

The generic name of Neurontin is gabapentin. Gabapentin serves as the non-proprietary or official name for the medication, distinct from the brand name Neurontin. Both drugs refer to the same active pharmaceutical ingredient.

Gabapentin, the generic version of Neurontin, is widely available and prescribed, offering a more affordable alternative to the brand name medication. As a generic name, gabapentin represents the standardized and universally recognized term used by healthcare professionals and pharmacists.

It’s important to note that various manufacturers produce gabapentin, resulting in different generic formulations that adhere to the same quality standards and specifications as the brand name Neurontin. The availability of gabapentin allows for greater accessibility and affordability for patients seeking the therapeutic benefits of this medication.

What is Neurontin used for?

Neurontin, known by its generic name gabapentin, is utilized for a range of medical conditions. Initially developed as an anticonvulsant for the management of epilepsy, the described drug has expanded its applications over time.

One prominent use of Neurontin is in the treatment of neuropathic pain, which includes conditions such as diabetic neuropathy, postherpetic neuralgia (nerve pain resulting from shingles), and peripheral neuropathy. Neurontin is thought to help modulate nerve signaling and alleviate the discomfort associated with these conditions.

In addition to its approved uses, it is prescribed off-label for various indications. These may include restless leg syndrome, fibromyalgia, certain anxiety disorders, and migraines. Off-label use refers to the prescription of a medication for a condition not officially listed in its approved indications, based on clinical judgment and evidence.

By affecting neurotransmitters and neuronal signaling, Neurontin aims to regulate abnormal electrical activity in the brain and modulate pain perception. It provides a potential avenue for individuals experiencing epilepsy, neuropathic pain, or other conditions where its therapeutic effects may prove beneficial.

How does Neurontin work?

The mechanism of action of Neurontin (gabapentin) involves various pharmacological effects on the central nervous system. Although the precise mechanism is not fully understood, several proposed actions contribute to its therapeutic effects. Here is a list of the proposed mechanisms of action:

  1. Binding to Alpha-2-delta Protein: This drug binds to the alpha-2-delta protein subunit of voltage-gated calcium channels in the brain. This interaction is thought to modulate the release of neurotransmitters, such as glutamate, reducing their release and subsequent excitatory signaling.
  2. Modulation of GABA Metabolism: It increases the synthesis and release of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in the brain. This increased GABAergic activity can help dampen abnormal neuronal firing and reduce excitability.
  3. Calcium Channel Regulation: Its binding to the alpha-2-delta protein subunit also regulates calcium channel trafficking and expression, potentially reducing the excitability of neurons.
  4. Glutamate Neurotransmission: It may indirectly inhibit the release of the excitatory neurotransmitter glutamate, which is involved in neuronal excitability. By modulating glutamate release, it can help balance excitatory and inhibitory neurotransmission.
  5. Neuroprotective Effects: Neurontin has been shown to possess neuroprotective properties in various experimental models. It may help protect against oxidative stress, inflammation, and excitotoxicity, which can contribute to neuronal damage or cell death.

How long does it take Neurontin to work?

The onset of action and the time it takes for Neurontin (gabapentin) to work can vary among individuals and depends on the specific condition being treated. It’s important to understand that Neurontin may not provide immediate relief and often requires a period of time to achieve its full therapeutic effect.

In some cases, it may start to exert its effects within a few days of initiating treatment. However, for certain conditions like neuropathic pain, it can take several weeks of consistent use to observe noticeable improvements.

Individual factors such as the dosage, treatment duration, metabolism, and the individual’s unique response to the medication can influence how quickly Neurontin takes effect. Additionally, the underlying condition being treated may also impact the time frame for experiencing the desired benefits.

How long does Neurontin stay in your system?

The duration that Neurontin (gabapentin) stays in the system can vary among individuals due to several factors, including metabolism, dosage, frequency of administration, and individual characteristics. Generally, it takes several days for this drug to be eliminated from the body.

The half-life of Neurontin, which is the time it takes for half of the drug to be cleared from the system, ranges from 5 to 7 hours in individuals with normal kidney function. Based on this half-life, it can be estimated that it may take approximately 1 to 2 days for it to be eliminated from the body completely.

It’s important to note that individual variations in metabolism and other factors can influence the clearance time of Neurontin. Additionally, for individuals with impaired kidney function, the elimination of Neurontin may be prolonged.

What is Neurontin dosage?

Dosage Form Strengths (mg)
Capsules 100 mg, 300 mg, 400 mg
Tablets 600 mg, 800 mg
Oral Solution 250 mg/5 mL, 500 mg/5 mL

The minimum and maximum doses of Neurontin can vary depending on the indication being treated. The dosages listed below are general guidelines and may not apply to all situations. It is crucial to consult with a healthcare professional for personalized dosage instructions.

For Epilepsy:

  • Starting Dose: 300 mg to 900 mg per day, divided into three doses.
  • Maintenance Dose: Typically ranges from 900 mg to 1800 mg per day, divided into three doses. Some individuals may require higher doses.

For Neuropathic Pain:

  • Starting Dose: 300 mg per day, divided into three doses or as prescribed by the healthcare provider.
  • Titration: The dose may be titrated up gradually over several weeks to achieve the desired pain relief. The maximum recommended dose can vary but is often in the range of 1800 mg to 3600 mg per day, divided into three doses.

Overdose

An overdose of Neurontin (gabapentin) occurs when an individual takes a higher dose of the medication than prescribed or intended, resulting in potentially harmful effects. It’s important to note that an overdose can be accidental or intentional, and immediate medical attention should be sought if an overdose is suspected.

Here is some information about an overdose:

  1. Symptoms: An overdose can lead to various symptoms, which may vary in severity. Common symptoms include drowsiness, sedation, dizziness, unsteady movements, slurred speech, confusion, and gastrointestinal disturbances such as nausea and vomiting. In severe cases, an overdose may cause respiratory depression, decreased heart rate, or even coma.
  2. Risk Factors: Certain factors can increase the risk of an overdose. These include taking higher doses than prescribed, combining Neurontin with other medications or substances that enhance its sedative effects (such as opioids or alcohol), and having a history of substance abuse or addiction.
  3. Treatment: If an overdose is suspected, it is crucial to seek immediate medical attention by calling emergency services or contacting a poison control center. Medical professionals will assess the situation and provide appropriate treatment. Treatment may involve supportive measures, such as monitoring vital signs, providing respiratory support if necessary, and managing symptoms.
  4. Prevention: To minimize the risk of an overdose, it is essential to take this drug exactly as prescribed by a healthcare professional. Avoid altering the dosage or frequency of use without medical guidance. It is also crucial to inform your healthcare provider about any other medications, supplements, or substances you are taking to prevent potential interactions.
  5. Education and Awareness: Patients prescribed Neurontin should be educated about the potential risks of an overdose and advised to store the medication securely, out of reach of children or individuals who may misuse it. Additionally, patients should be aware of the signs and symptoms of an overdose to seek prompt medical attention if needed.

What are contraindications?

Strict Contraindications Unstrict Contraindications
Hypersensitivity or Allergy Respiratory Depression
Geriatric Patients
Psychiatric Disorders
Pregnancy and Breastfeeding
Liver Impairment

What are the side effects?

Common Side Effects Rare Side Effects
Drowsiness or sedation Mood changes (irritability, depression)
Fatigue Changes in appetite
Dizziness or lightheadedness Tremor
Peripheral edema (swelling) Allergic reactions (rash, itching, swelling)
Weight gain Cognitive impairment (memory, concentration)

What are drug interactions?

Neurontin (gabapentin) may interact with certain medications, substances, or medical conditions. It’s important to inform your healthcare provider about all the medications, supplements, and medical conditions you have before starting the therapy. Here are some notable drug interactions associated with Neurontin:

  1. Antacids: Taking this drug with antacids containing aluminum and magnesium hydroxide may reduce the absorption of Neurontin. It is recommended to separate the doses by at least 2 hours.
  2. Opioids: Combining this drug with opioids, such as morphine or oxycodone, may increase the risk of central nervous system (CNS) depression and respiratory depression. Close monitoring is advised when using these medications together.
  3. CNS Depressants: This drug can enhance the sedative effects of other CNS depressants, including benzodiazepines, sedatives, muscle relaxants, and certain antidepressants. Caution should be exercised, and dosage adjustments may be necessary when using Neurontin alongside these medications.
  4. Naproxen: Concurrent use of Neurontin and naproxen (a nonsteroidal anti-inflammatory drug) may increase the blood levels of gabapentin. Dose adjustments may be required.
  5. Alcohol: Combining Neurontin with alcohol can increase the risk of central nervous system depression, drowsiness, dizziness, and impaired coordination. It is generally advised to avoid or limit alcohol consumption while taking Neurontin.
  6. Opioid Withdrawal: Abrupt discontinuation of opioids in individuals using Neurontin for opioid withdrawal syndrome can increase the risk of seizures. Careful monitoring and appropriate dosage adjustments are recommended in such cases.

What are withdrawal symptoms?

Withdrawal symptoms can vary depending on the substance involved and the individual’s physiology, duration and intensity of substance use, and other factors. Common withdrawal symptoms may include:

  1. Physical Symptoms: These can include nausea, vomiting, sweating, tremors, muscle aches, headaches, rapid heartbeat, changes in blood pressure, and gastrointestinal disturbances.
  2. Psychological Symptoms: These may manifest as anxiety, irritability, mood swings, depression, restlessness, difficulty concentrating, insomnia, and intense cravings for the substance.
  3. Sleep Disturbances: Insomnia or disturbed sleep patterns are common during withdrawal. It may be challenging to fall asleep or stay asleep throughout the night.
  4. Fatigue and Lack of Energy: Individuals undergoing withdrawal often experience extreme tiredness, lack of energy, and reduced motivation.
  5. Cognitive Impairment: Withdrawal can affect cognitive function, resulting in difficulties with memory, attention, and decision-making.
  6. Emotional Instability: Emotional instability and heightened sensitivity to stress or emotional triggers are common during withdrawal.

Gabapentin vs Neurontin

Neurontin is the brand name for the medication gabapentin. Neurontin and gabapentin refer to the same active ingredient, with Neurontin being the brand name under which gabapentin is marketed. They are pharmacologically equivalent, meaning they have the same chemical composition and therapeutic effects.

Both drugs are used interchangeably to treat conditions such as epilepsy, neuropathic pain, and other off-label uses. While Neurontin is the specific brand name, generic versions of gabapentin are also available.

The similarities between Neurontin and gabapentin lie in their shared active ingredient (gabapentin), therapeutic effects, pharmacokinetics, and safety profiles. They are both anticonvulsant medications used for epilepsy, neuropathic pain, and other off-label conditions.

The main difference lies in their availability and cost. Neurontin is the brand name medication marketed by a specific pharmaceutical company and tends to be more expensive. On the other hand, gabapentin is the generic version available from multiple manufacturers, which often makes it more affordable.

Neurontin pricing

  1. Branded Neurontin:
    • Monthly supply (30 capsules) could range from approximately $100 to $300 or more, depending on the dosage and location.
  2. Generic Gabapentin:
    • Monthly supply (30 capsules) could range from approximately $10 to $100 or more, depending on the dosage and location.

FAQs

Q: Why is Neurontin a controlled substance?
A: Neurontin is not classified as a controlled substance, narcotic, or addictive medication. It does not have the same potential for abuse or dependence as substances classified as controlled substances. However, it’s important to follow the prescribed dosage and usage instructions provided by a healthcare professional to ensure safe and effective use.

Q: Neurontin for dogs – yes or no?
A: Neurontin can be used in veterinary medicine to treat certain conditions in dogs, such as epilepsy or chronic pain. However, the use of this drug for dogs should always be under the guidance and prescription of a veterinarian. Dosage, administration, and considerations specific to dogs should be determined by a veterinary professional.

Q: Is Neurontin a good painkiller?
A: Neurontin can be effective in managing certain types of chronic pain, particularly neuropathic pain. It modulates nerve signaling and may help alleviate pain associated with conditions such as diabetic neuropathy or postherpetic neuralgia. However, its effectiveness may vary among individuals, and other pain management options should be considered based on the specific type and severity of pain.

Q: Does Neurontin make you sleepy?
A: Drowsiness and sedation are common side effects of this drug. While not everyone will experience this, some individuals may feel sleepy or experience drowsiness, especially when initiating treatment or with higher doses. It is important to be cautious when engaging in activities requiring alertness until you know how Neurontin affects you personally.

Q: Neurontin and alcohol – possible or not?
A: The combination of Neurontin and alcohol is generally not recommended. Both substances can have sedative effects on the central nervous system (CNS). Combining the two may increase the risk of excessive sedation, drowsiness, impaired coordination, and other adverse effects. It is advisable to consult with a healthcare professional regarding alcohol consumption while the treatment.

Q: Does Neurontin cause weight gain?
A: Weight gain has been reported as a possible side effect of the drug’s use. However, not everyone will experience weight gain, and the extent of weight gain may vary. Factors such as individual metabolism, lifestyle, and concurrent medications can influence any potential weight changes. It is important to monitor your weight and discuss any concerns with your healthcare professional.

Neurontin reviews

Sarah Johnson
Rating: *****
Neurontin has been a game-changer for my epilepsy management. It has significantly reduced the frequency and intensity of my seizures. I’m grateful for the positive impact it has had on my life.

Michael Thompson
Rating: ***
Neurontin helped alleviate my nerve pain to some extent, but I experienced drowsiness as a side effect. It took time to find the right dosage that balanced pain relief and tolerable side effects.

Emily Davis
Rating: ****
I’ve been taking Neurontin for neuropathic pain, and it has made a noticeable difference. My pain levels have reduced, allowing me to engage in daily activities more comfortably. The only downside is occasional dizziness.

David Ramirez
Rating: **
Unfortunately, Neurontin didn’t provide much relief for my restless leg syndrome. I didn’t notice a significant improvement in my symptoms, and the side effects, such as drowsiness, were bothersome.

Olivia Parker
Rating: *****
Neurontin has been a lifesaver for my fibromyalgia. It has significantly reduced my pain levels and improved my quality of life. The only downside is feeling a bit tired occasionally.

Benjamin Lee
Rating: ****
Neurontin has been effective for my postherpetic neuralgia pain. It took a few weeks to start noticing the effects, but the reduction in pain has been worth it. Mild drowsiness is the only side effect I’ve experienced.

Ava Robinson
Rating: ****
Neurontin has helped manage my anxiety disorder surprisingly well. It has reduced my anxiety levels, allowing me to feel more at ease in social situations. The initial dizziness subsided after a couple of weeks.

William Baker
Rating: ***
Neurontin has provided moderate relief for my migraine attacks. While it hasn’t eliminated them entirely, the frequency and severity have decreased. However, I did experience some mild drowsiness initially.

Sophia Collins
Rating: *****
Neurontin has been a godsend for my diabetic neuropathy. It has significantly reduced the burning and tingling sensations in my feet. The initial drowsiness subsided, and I’ve been able to manage it well.

Disclaimer: The information provided in this article is based on general knowledge and research and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Individuals with underlying medical conditions, taking other medications, or experiencing prolonged or severe symptoms of erectile dysfunction should seek advice from a healthcare professional before using any medication. The author and publisher of this article do not endorse or promote the use of any particular medication and disclaim any liability for the use or interpretation of information presented herein. Always consult with a healthcare professional before making any changes to your medical treatment or medication regimen.